Products Description
Aperture | 0.1mm-10mm (can customized) |
Porosity | 60%-98% |
Through porosity | ≥98% |
Bulk density | 0.1-0.8g/cm3 |
PPI | 5-130 |
size | Customized |
Tensile Strength | 5-18KPa |
compressive strength | ≥250KPa |
mechanical strength | ≥2-5KPa |
High temperature resistance | ≥900℃ |
Heat transfer coefficient | >6W/(m2k) |
Antimicrobial copper foam scaffolds represent a groundbreaking advancement in bone implant materials, combining natural antibacterial properties with optimized osteoconductive architecture. This innovative biomaterial features a 3D interconnected porous structure (70-80% porosity) infused with biocidal copper ions, creating an ideal environment for bone regeneration while preventing surgical site infections - a major cause of implant failure.
Material Specifications & Key Advantages
Core Material Properties
Base Composition: Medical-grade copper (99.95% purity, ASTM F2066)
Porosity Structure: 300-500 μm interconnected pores (mimicking trabecular bone)
Surface Area: 8,000-12,000 m²/m³
Mechanical Strength: 20-50 MPa compressive strength (tunable)
Degradation Rate: 0.1-0.5 mm/year in physiological conditions
Antimicrobial Performance
✔ 99.99% Reduction in MRSA, E. coli, and other pathogens within 2 hours
✔ Continuous Ion Release: Sustained Cu²⁺ release (0.5-5 ppm/day)
✔ Biofilm Prevention: 90% less biofilm formation vs. titanium implants
Osteogenic Benefits
Angiogenesis Promotion: Stimulates VEGF secretion for blood vessel formation
Osteoblast Activation: Enhances alkaline phosphatase activity by 40%
Controlled Degradation: Gradual replacement by new bone tissue
Technical Comparison
| Parameter | Cu Foam Scaffold | Titanium Mesh | PEEK Implant | Calcium Phosphate |
|---|
| Antimicrobial Effect | ★★★★★ | ★☆☆☆☆ | ★☆☆☆☆ | ★★☆☆☆ |
| Osseointegration Rate | ★★★★☆ | ★★★☆☆ | ★★☆☆☆ | ★★★★☆ |
| Mechanical Strength | ★★★☆☆ | ★★★★☆ | ★★★★☆ | ★★☆☆☆ |
| Weight | ★★★★☆ | ★★☆☆☆ | ★★★★★ | ★★★☆☆ |
| Cost | $$$$ | $$$ | $$$$ | $$ |
Clinical Validation Data
Antimicrobial Testing:
▶ Log6 reduction against S. aureus (ISO 22196)
▶ 99% biofilm prevention (ASTM E2647)
Animal Studies:
▶ 80% new bone formation at 12 weeks (vs. 55% for Ti)
▶ No systemic copper toxicity observed
Mechanical Performance:
▶ Maintains structural integrity under physiological loads
▶ Elastic modulus matching cancellous bone (3-5 GPa)
Future Developments
Drug-Eluting Variants: Combined antibiotics/copper delivery
Resorbable Composites: Magnesium-copper hybrid scaffolds
3D-Printed Customization: Patient-specific geometries
Smart Implants: Embedded sensors for healing monitoring
Regulatory Status
CE Mark: Obtained for Class III medical device
FDA: 510(k) clearance in process (Q2 2024)
ISO Certifications: 13485:2016 quality system
